????????????????
?NEJM??????????????????????????????????????????????????????????????????
???????????????????????????155?????90?????????????????????????????????????64????????????49??????????????????23.4??28.6????????????????????????????????????????????5.6?????????????????????????
?Valvular Heart Disease and the Use of Dopamine Agonists for Parkinson’s Disease
????N Engl J Med 2007 Jan 4; 356:39-46?
?????http://content.nejm.org/cgi/content/abstract/356/1/39
????????????????????????????????????????11,417????????????????????????????????????????????????????????7.1????????????????????37?????????????????????4.9????????????????50.3?????????????????????????????????????????????????????????????????????????????????????????????????
?Dopamine Agonists and the Risk of Cardiac-Valve Regurgitation
??N Engl J Med 2007 Jan 4; 356:29-38?
?????http://content.nejm.org/cgi/content/abstract/356/1/29
????????????????????????????5-HT?????????????????1997????????????????5-HTB2??????????????????????????????????????????????????????????????5-HTB2??????????????????????????????
??????????????????2003???????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????FDA???????????????????????????
?????????????????????Foodconsumer.org 1?3?
?Parkinson�s drugs may be riskier than thought
???MSNBC?2007.1.3?AP?????
???http://www.msnbc.msn.com/id/16454843/
?Heart-Valve Disease Linked to Two Parkinson’s Drugs
???Medpage TODAY 2007.1.4?
???http://www.medpagetoday.com/Cardiology/AcuteCoronarySyndrome/tb/4801
1?4?18?10????5?14?20???