PPI??????????????????
??????????????????PPI????????????PPI?????????????????????????????????CMAJ ?????????????
?PPI??????????????????2?????study??????????????????????????????????????
?Use of proton pump inhibitors and risk of osteoporosis-related fractures
??CMAJ 2008 179: 319-326.?
??http://www.cmaj.ca/cgi/content/abstract/179/4/319
??http://www.cmaj.ca/cgi/content/full/179/4/319
???????1996?4???2004?3??????????????50????????63,000?????????????????????????????????????16,000?????????????????PPI????????????????????????????????????????????????????????OTC?????????????????????????????
???????????PPI???????????????????????7????????????????2?????????????hip fracture?????????5???????62??7?????????????4???????????
????????PPI??????????????????????????????????????????????????????????????????????
????????????????????????????????????????????????PPI???????????????????????????????????
?CMAJ ????Commentary????????????????????????????????????????????????????3?????PPI??????????????????????????????????????????????????????PPI??????????????
Proton pump inhibitors: balancing the benefits and potential fracture risks
??CMAJ 2008 179: 306-307.?
??http://www.cmaj.ca/cgi/content/full/179/4/306
??????
TOPICS 2006.12.28?PPI???????????????????????(????)
Proton pump inhibitors, histamine H2 receptor antagonists, and other antacid medications and the risk of fracture.
?????Calcif Tissue Int. 2006 Aug;79(2):76-83.?
???http://www.ncbi.nlm.nih.gov/pubmed/16927047
???Nexium, similar prescription antacids may boost bone-fracture risk: study
?The Canadian Press????2008.8.11?
???http://www.canadaeast.com/wellness/article/381092
Powerful Antacid Drugs Raise Fracture Risk?Healthday 2008.8.12?
???http://www.healthday.com/Article.asp?AID=618291
????TGA??2????�Australian Adverse Drug Reactions Bulletin�???????????????????PPI??????????????????2????????????????hip fracture???????????????????????????????PPI???????????????????????????????????
Proton pump inhibitors and possible fracture risk
?Australian Adverse Drug Reactions Bulletin Vol.28, Number 1, February 2009?
?http://www.tga.health.gov.au/adr/aadrb/aadr0902.htm
投稿者 by ???????? — 2009年2月2日(月)09:29