????NSAID??????????
?????????????????NSAID??????????????Alzheimer dementia,AD?????????????????????(TOPICS?2008.05.07)???????????????????????????????????????????study????????????????????????????????????????????????????????
| ??? ????? |
NSAIDs?AD????????? |
|---|---|
| ????? | community-based cohort study |
| ???????????? | ?????????????????????????????????65???????2736??????74.8????90?????? |
| ????? | NSAID??????????????????????????????????80??????????????2?????NSAID??????????????????500???????????????????????????????????????????????? ????????351??12.8???NSAID?????????????12???????107??3.9???NSAID?????????????? |
| ????? | AD?????12?????? |
| ?????? | 476???????????356??????????? ??????????????????????????NSAID???????????NSAIDs??????????????????????????66?????????????????57??????? |
| ??????? | ????????????????????????????????????????????????NSAID??AD?????????????????????????????????NSAID?????????????????????????????????????? |
| ????? | Risk of dementia and AD with prior exposure to NSAIDs in an elderly community-based cohort |
| ???? | Neurology Published online before print April 22, 2009 |
| ????? | http://www.neurology.org/cgi/content/abstract/WNL.0b013e3181a18691v1 |
?????TOPICS?2008.05.07?NSAIDS???????????????
???????
Painkiller ‘no Alzheimer’s block’?BBC NEWS 2009.4.22?
?http://news.bbc.co.uk/2/hi/health/8010295.stm
Painkillers Do Not Delay Dementia in the Very Elderly
??Medical News TODAY 2009.4.22?
?http://www.medicalnewstoday.com/articles/147201.php
Painkillers May Not Protect Against Dementia
??HealthDay 2009.4.22?
??http://www.healthday.com/printer.asp?AID=626322
Heavy NSAID Use Linked to Higher Dementia Risk
??Medpage TODAY 2009.4.22?
??http://www.medpagetoday.com/Psychiatry/AlzheimersDisease/13860