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2009年6月11日(木)

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投稿者: ????????

????????????????????????????????????????????????????????????????????????????????????????????????????????????????????NEJM ???????????

???????study????????????????????????????????????????????????????????

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???????????????????????????????????
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???????????? ??????????Soroka Medical Center?????????15?49????81?703?????
????? ??????????????????????????3,458??
????? ??????????????????????????78,245??
?????? ???????????????????????????????????????????????????????????????? vs ????? 

????? (OR 1.04, 95% CI 0.89 to 1.21)(5.3% vs 4.9%)
????? (OR 1.10, 95% CI 0.92 to 1.31)
??????? (OR 1.01, 95% CI 0.89 to 1.14)(8.5% vs 8.3%)
?? (OR 1.15, 95% CI 0.99 to 1.34)(6.3% vs 5.9%)
?????? (OR 0.87, 95% CI 0.55 to 1.38)(1.5% vs 2.2%)
1??????????? (OR 0.97, 95% CI 0.84 to 1.13)
5??????????? (OR 0.84, 95% CI 0.57 to 1.22)

??????? ??????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????????
????? The Safety of Metoclopramide Use in the First Trimester of Pregnancy
????? N Engl J Med 2009; 360: 2528-35.
????? http://content.nejm.org/cgi/content/abstract/360/24/2528

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????????????????????????
?http://memoru.babymilk.jp/ninnsinn/akatyan/apgar.html

TOPICS?2009.02.28????????????????????????????FDA?

???????
?Antiemetic Agent Safe During First Trimester of Pregnancy
? ?(Medpage TODAY 2009.6.09)
??http://www.medpagetoday.com/OBGYN/Pregnancy/14644
?Morning sickness drug shown safe for babies
???MSNBC 2009.6.10 AP???
??http://www.msnbc.msn.com/id/31208741/
?Study: A Safe Drug for Morning Sickness??TIMES 2009.6.10?
??http://www.time.com/time/health/article/0,8599,1903944,00.html

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