??????????????????????????FDA?
?PPI??????????????????????????????????????????TOPICS 2009.01.29????????????17??FDA???????????????????????????PPI?????????????????????????????
Updated Safety Information about a drug interaction between Clopidogrel Bisulfate (marketed as Plavix) and Omeprazole (marketed as Prilosec and Prilosec OTC)
?FDA 2009.11.17 Public Health Advisory ?
http://www.fda.gov/Drugs/DrugSafety/PublicHealthAdvisories/ucm190825.htm
??????????????????Vol.7 No.25??????????
http://www.nihs.go.jp/dig/sireport/weekly7/25091210.pdf
Update to the labeling of Clopidogrel Bisulfate (marketed as Plavix) to alert healthcare professionals about a drug interaction with omeprazole (marketed as Prilosec and Prilosec OTC)
?FDA 2009.11.17 Information for Healthcare Professionals?
?FDA???Sanofi-Aventis ?? Bristol-Myers Squibb ???????????????????????????????????????CYP2C19????????????????????????????????
????????????????????????????45?????????47????????????????????????12??????????????????????
????????FDA?????????????????
- ????????????????????????????????????
- ????????????????????????????????????????????OTC???????????????????
- ?????????????????????????????????????????????????????????
- ?????????????????????????????OTC?????????????????????????
????????????????????????????????
- esomeprazole????????????????????
- ???????PPI????????????????????????????
- ??????????????????????voriconazole?etravirine?felbamate??????????????????????????CYP2C19??????????????????????????????????????
PLAVIX?FDA Label Information 2009.11.12?
http://www.accessdata.fda.gov/drugsatfda_docs/label/2009/020839s044lbl.pdf
?Healt? Day ??????????????????????????????????????????????????????????
?????TOPICS?2009.01.29?PPI??????????????????????
???Heartburn Drugs Can Thwart Popular Blood Thinner
????Health Day?2009.11.17?
????http://www.healthday.com/Article.asp?AID=633204
12?10??????
?????????????????????????
????????????????????LANCET????????????????????????????????????????????????????
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(09)61525-7/abstract
??????????????????????????????????
????????
http://chuopharm.dtiblog.com/
Åê¹Æ¼Ô by ???????? — 2009ǯ11·î18Æü(¿å)15:54
???????????????
?????????????????????????????????????
?????????????????????Label Information ??????????????????????????????????????????
???????????????????????????????????????LANCET???????????????
??AP??????????????? Public Citizen ????????????????“black box”warning label????????????????
?????????????????????????????????
FDA says heartburn drugs can interfere with Plavix
??CNBC 2009.11.17 AP???
?http://www.cnbc.com/id/33991224
Åê¹Æ¼Ô by ???????? — 2009ǯ11·î18Æü(¿å)17:20