?????????????????????
????????EMEA?European Medicines Agency??21???????????????????????Meridia??????????????????????????????????????????????????????
European Medicines Agency recommends suspension of marketing authorisations for sibutramine?EMEA?2010.1.21?
http://www.ema.europa.eu/pdfs/human/referral/sibutramine/3940810en.pdf
Questions and answers on the suspension of medicines containing sibutramine?EMEA?2010.1.21?
http://www.ema.europa.eu/pdfs/human/referral/sibutramine/Sibutramine_Q&A_80817909en.pdf
????????????????Vol.8 No.3??????????
http://www.nihs.go.jp/dig/sireport/weekly8/04100218.pdf
??????????????????????????????????????????????????EMEA???????CHMP?9800?????6?????????SCOUT study (Sibutramine Cardiovascular Outcome Trial)???????????????????????????????????????????????????
?????EMEA?????????????????
- ??????????????????????????????????????
- ???????????????????????????
- ??????????????????????????????????
- ?????????????????????????????????
- ?????????????????????????
??????????????MHRA????????????????
Sibutramine: Suspension of marketing authorisation as risks outweigh benefits?MHRA?2010.1.21?
Suspension of sibutramine (Reductil)?MHRA?2010.1.21?
?http://www.mhra.gov.uk/NewsCentre/CON068470
????????????????????????????????????????????????????????????????????????????????????????????????????
????????OTC????????????????Alli????????????????????????????????????
FDA Warns Consumers about Counterfeit Alli
The counterfeit products contain controlled substance sibutramine
?FDA?NEWS RELEASE?2010.1.18?
http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm197857.htm
??????????11????????????Early Communication ??????????????????????????????????????
Early Communication about an Ongoing Safety Review of Meridia (sibutramine hydrochloride)?FDA?2009.11.20?
????????????????????????????????????????????????BMI25????????????????????????????????????????????????????????????????7?24??????????????????????????9?29??????????????????????????????
?????????????????????????????????????????
?????TOPICS
?2008.10.27?????Orlistat??????????
?2010.01.21??????? ????????Vol.8 No.2
???
Top obesity drug sibutramine being withdrawn
?BBC NEWS 2010.1.22 UPDATE?
?http://news.bbc.co.uk/2/hi/health/8473555.stm
???ONLINE?2009?7?27?
?http://www.mixonline.jp/Article/tabid/55/artid/37679/Default.aspx
????WEB??????10?6?
?http://nk.jiho.jp/servlet/nk/gyosei/article/1226551893481.html?pageKind=outline
2?18??????
?????????????????FDA?21????11?? Early Communication ? follow-up?????????
Follow-Up to the November 2009 Early Communication about an Ongoing Safety Review of Sibutramine, Marketed as Meridia?FDA 2010.1.21?
Meridia (sibutramine hydrochloride): Follow-Up to an Early Communication about an Ongoing Safety Review?FDA 2010.1.21?
FDA?????????????????????????????????????
???????????????
???????????????????????
????????????
????????????????
????????????
???????????????????145/90???
?????????????????????????3?????????????????????????????????????
投稿者 by ???????? — 2010年1月22日(金)15:04